Systems | Information | Learning | Optimization
 

Backward Feature Correction: How can Deep Learning performs Deep Learning

How does a 110-layer ResNet learn a high-complexity classifier using relatively few training examples and short training time? We present a theory towards explaining this learning process in terms of hierarchical learning. We refer to hierarchical learning as the learner learns to represent a complicated target function by decomposing it into a …

Biologically interpretable machine learning modeling for understanding functional genomics

Robust phenotype-genotype associations have been established for a number of human diseases including brain disorders (e.g., schizophrenia, bipolar disorder). However, understanding the cellular and molecular causes from genotype to phenotype remains elusive. To address this, recent scientific projects have generated large multi-omic datasets — e.g., the PsychENCODE consortium generated ~5,500 genotype, …